alpha-synuclein inclusion body_Snca<tm1Nbm>/Snca<tm1Nbm>,Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm,Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm

http://metadb.riken.jp/0008493I129S6SvEvTacFVBNSncatm1NbmSncatm1NbmTgSNCAA53T1NbmTgSNCAA53T1NbmTgSNCAA53T2NbmTgSNCAA53T2NbmSncatm1NbmTgSNCAA53T2NbmTgSNCAA53T1Nbm

alpha-synuclein inclusion body_Snca<tm1Nbm>/Snca<tm1Nbm>,Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm,Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Robert L Nussbaum
  http://metadb.riken.jp/db/mgi_rdf/MGI:4412062
• transgene insertion 2, Robert L Nussbaum
  http://metadb.riken.jp/db/mgi_rdf/MGI:4412064
• synuclein, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277151

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Snca<tm1Nbm>/Snca<tm1Nbm>,Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm,Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Snca<tm1Nbm>|Tg(SNCA*A53T)2Nbm|Tg(SNCA*A53T)1Nbm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• alpha-synuclein inclusion body
  http://purl.obolibrary.org/obo/MP_0008493

文献

http://purl.org/net/cito/citesAsAuthority

• Yien-Ming. Kuo, et.al., Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes., Human molecular genetics, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20106867