decreased IgG2a level_Map4k3<Gt(RRO270)Byg>/Map4k3<Gt(RRO270)Byg>

http://metadb.riken.jp/0008496I129P2OlaHsdMap4k3GtRRO270BygMap4k3GtRRO270BygMap4k3GtRRO270Byg

decreased IgG2a level_Map4k3<Gt(RRO270)Byg>/Map4k3<Gt(RRO270)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase kinase kinase kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2154405

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map4k3<Gt(RRO270)Byg>/Map4k3<Gt(RRO270)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Map4k3<Gt(RRO270)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased IgG2a level
  http://purl.obolibrary.org/obo/MP_0008496

文献

http://purl.org/net/cito/citesAsAuthority

• Huai-Chia. Chuang, et.al., The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells., Nature immunology, 2011, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21983831