increased IgG1 level_Klf2<tm2Ling>/Klf2<tm2Ling>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0008499I129S6SvEvTacC57BL6DBA2Klf2tm2LingKlf2tm2LingTgCd4cre1CwiTgCd4cre1CwiKlf2tm2Ling

increased IgG1 level_Klf2<tm2Ling>/Klf2<tm2Ling>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kruppel-like factor 2 (lung)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342772
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Klf2<tm2Ling>/Klf2<tm2Ling>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Klf2<tm2Ling>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgG1 level
  http://purl.obolibrary.org/obo/MP_0008499

文献

http://purl.org/net/cito/citesAsAuthority

• Michael A. Weinreich, et.al., KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors., Immunity, 2009, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/19592277