increased IgG2a level_Fas<lpr>/Fas<lpr>,Itfg2<Gt(OST215121)Lex>/Itfg2<Gt(OST215121)Lex>

http://metadb.riken.jp/0008500I129S5SvEvBrdC57BL6JMRLMpFaslprFaslprItfg2GtOST215121LexItfg2GtOST215121LexItfg2GtOST215121LexFaslpr

increased IgG2a level_Fas<lpr>/Fas<lpr>,Itfg2<Gt(OST215121)Lex>/Itfg2<Gt(OST215121)Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fas (TNF receptor superfamily member 6)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95484
• integrin alpha FG-GAP repeat containing 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915450

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fas<lpr>/Fas<lpr>,Itfg2<Gt(OST215121)Lex>/Itfg2<Gt(OST215121)Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itfg2<Gt(OST215121)Lex>|Fas<lpr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * C57BL/6J * MRL/Mp

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgG2a level
  http://purl.obolibrary.org/obo/MP_0008500

文献

http://purl.org/net/cito/citesAsAuthority

• Amin. Al-Shami, et.al., Integrin-α FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus model., Journal of immunology (Baltimore, Md. : 1950), 2013, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/23997217