increased IgG2a level_Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>/Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>,Tg(CD2-icre)4Kio/0

http://metadb.riken.jp/0008500IC57BL6C57BL10CBACaGtROSA26Sortm3CAGMIR1792EGFPRskyGtROSA26Sortm3CAGMIR1792EGFPRskyTgCD2icre4Kio0TgCD2icre4KioGtROSA26Sortm3CAGMIR1792EGFPRsky

increased IgG2a level_Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>/Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>,Tg(CD2-icre)4Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 4, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449946

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>/Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>,Tg(CD2-icre)4Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD2-icre)4Kio|Gt(ROSA)26Sor<tm3(CAG-MIR17-92,-EGFP)Rsky>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgG2a level
  http://purl.obolibrary.org/obo/MP_0008500

文献

http://purl.org/net/cito/citesAsAuthority

• Changchun. Xiao, et.al., Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18327259