polycystic kidney_Pkd2<tm1Som>/Pkd2<tm2Som>

http://metadb.riken.jp/0008528I129SvC57BL6JSJLPkd2tm1SomPkd2tm2SomPkd2tm1SomPkd2tm2Som

polycystic kidney_Pkd2<tm1Som>/Pkd2<tm2Som>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polycystic kidney disease 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099818

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pkd2<tm1Som>/Pkd2<tm2Som>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pkd2<tm1Som>|Pkd2<tm2Som>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• polycystic kidney
  http://purl.obolibrary.org/obo/MP_0008528

文献

http://purl.org/net/cito/citesAsAuthority

• Vladimir G. Gainullin, et.al., Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner., The Journal of clinical investigation, 2015, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/25574838
• Angela. Stroope, et.al., Hepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease., The American journal of pathology, 2010, 176
  http://rdf.ncbi.nlm.nih.gov/pubmed/20093497
• G. Wu, et.al., Cardiac defects and renal failure in mice with targeted mutations in Pkd2., Nature genetics, 2000, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/10615132
• G. Wu, et.al., Somatic inactivation of Pkd2 results in polycystic kidney disease., Cell, 1998, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/9568711