increased chemical nociceptive threshold_Hcn2<tm1.1Lex>/Hcn2<tm1.1Lex>,Scn10a<tm2(cre)Jnw>/Scn10a<+>

http://metadb.riken.jp/0008531I129C57BL6Hcn2tm11LexHcn2tm11LexScn10atm2creJnwScn10aScn10aHcn2tm11LexScn10atm2creJnw

increased chemical nociceptive threshold_Hcn2<tm1.1Lex>/Hcn2<tm1.1Lex>,Scn10a<tm2(cre)Jnw>/Scn10a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hyperpolarization-activated, cyclic nucleotide-gated K+ 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298210
• sodium channel, voltage-gated, type X, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:108029

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hcn2<tm1.1Lex>/Hcn2<tm1.1Lex>,Scn10a<tm2(cre)Jnw>/Scn10a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn10a<+>|Hcn2<tm1.1Lex>|Scn10a<tm2(cre)Jnw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased chemical nociceptive threshold
  http://purl.obolibrary.org/obo/MP_0008531

文献

http://purl.org/net/cito/citesAsAuthority

• Edward C. Emery, et.al., HCN2 ion channels play a central role in inflammatory and neuropathic pain., Science (New York, N.Y.), 2011, 333
  http://rdf.ncbi.nlm.nih.gov/pubmed/21903816