increased susceptibility to induced colitis_Myd88<tm1Aki>/Myd88<tm1Aki>,Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0008537I129P2OlaHsdC57BL6SJLMyd88tm1AkiMyd88tm1AkiTnfaip3tm11GvlTnfaip3tm11GvlTgVil1cre997Gum0TgVil1cre997GumTnfaip3tm11GvlMyd88tm1Aki

increased susceptibility to induced colitis_Myd88<tm1Aki>/Myd88<tm1Aki>,Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• myeloid differentiation primary response gene 88
  http://metadb.riken.jp/db/mgi_rdf/MGI:108005
• tumor necrosis factor, alpha-induced protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1196377

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Myd88<tm1Aki>/Myd88<tm1Aki>,Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Tnfaip3<tm1.1Gvl>|Myd88<tm1Aki>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to induced colitis
  http://purl.obolibrary.org/obo/MP_0008537

文献

http://purl.org/net/cito/citesAsAuthority

• Lars. Vereecke, et.al., Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20530205