increased susceptibility to induced colitis_Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0008537I129S2SvPasC57BL6SJLTnfaip3tm11GvlTnfaip3tm11GvlTnfrsf1atm1MakTnfrsf1atm1MakTgVil1cre997Gum0TgVil1cre997GumTnfrsf1atm1MakTnfaip3tm11Gvl

increased susceptibility to induced colitis_Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884
• tumor necrosis factor, alpha-induced protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1196377

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnfaip3<tm1.1Gvl>/Tnfaip3<tm1.1Gvl>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Tnfrsf1a<tm1Mak>|Tnfaip3<tm1.1Gvl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to induced colitis
  http://purl.obolibrary.org/obo/MP_0008537

文献

http://purl.org/net/cito/citesAsAuthority

• Lars. Vereecke, et.al., Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20530205