abnormal neocortex morphology_Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Slc32a1-cre)65Kzy/0

http://metadb.riken.jp/0008547I129P2OlaHsdC57BL6Scn1atm21KzyScn1atm21KzyTgSlc32a1cre65Kzy0TgSlc32a1cre65KzyScn1atm21Kzy

abnormal neocortex morphology_Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Slc32a1-cre)65Kzy/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98246
• transgene insertion 65, Kazuhiro Yamakawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:5523785

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn1a<tm2.1Kzy>/Scn1a<tm2.1Kzy>,Tg(Slc32a1-cre)65Kzy/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Slc32a1-cre)65Kzy|Scn1a<tm2.1Kzy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neocortex morphology
  http://purl.obolibrary.org/obo/MP_0008547

文献

http://purl.org/net/cito/citesAsAuthority

• Ikuo. Ogiwara, et.al., Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome., Human molecular genetics, 2013, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23922229