increased circulating tumor necrosis factor level_Rag1<tm1Mom>/Rag1<tm1Mom>,Sh3bp2<tm1Bjro>/Sh3bp2<tm1Bjro>

http://metadb.riken.jp/0008553I129S4SvJae129S7SvEvBrdBALBcJC57BL6JRag1tm1MomRag1tm1MomSh3bp2tm1BjroSh3bp2tm1BjroRag1tm1MomSh3bp2tm1Bjro

increased circulating tumor necrosis factor level_Rag1<tm1Mom>/Rag1<tm1Mom>,Sh3bp2<tm1Bjro>/Sh3bp2<tm1Bjro>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• SH3-domain binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346349

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag1<tm1Mom>/Rag1<tm1Mom>,Sh3bp2<tm1Bjro>/Sh3bp2<tm1Bjro>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag1<tm1Mom>|Sh3bp2<tm1Bjro>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/cJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating tumor necrosis factor level
  http://purl.obolibrary.org/obo/MP_0008553

文献

http://purl.org/net/cito/citesAsAuthority

• Yasuyoshi. Ueki, et.al., Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice., Cell, 2007, 128
  http://rdf.ncbi.nlm.nih.gov/pubmed/17218256