decreased tumor necrosis factor secretion_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

http://metadb.riken.jp/0008561I129S2SvPasC57BL6Casp1tm1FlvCasp1tm1FlvCasp4delCasp4delCasp4delCasp1tm1Flv

decreased tumor necrosis factor secretion_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96544
• caspase 4, apoptosis-related cysteine peptidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:107700

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp4<del>|Casp1<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor necrosis factor secretion
  http://purl.obolibrary.org/obo/MP_0008561

文献

http://purl.org/net/cito/citesAsAuthority

• K. Kuida, et.al., Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme., Science (New York, N.Y.), 1995, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/7535475