increased interferon-gamma secretion_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Lck-cre)1Jtak/0

http://metadb.riken.jp/0008566I129S1Sv129X1SvJHif1atm3RsjoHif1atm3RsjoTgLckcre1Jtak0TgLckcre1JtakHif1atm3Rsjo

increased interferon-gamma secretion_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Lck-cre)1Jtak/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3655253
• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(Lck-cre)1Jtak/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)1Jtak|Hif1a<tm3Rsjo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008566

文献

http://purl.org/net/cito/citesAsAuthority

• Dmitriy. Lukashev, et.al., Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 2006, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/17015677