decreased interferon-gamma secretion_Il12b<tm1Jm>/Il12b<tm1Jm>,Il18<tm1Aki>/Il18<tm1Aki>

http://metadb.riken.jp/0008567I129P2OlaHsd129S1SvImJIl12btm1JmIl12btm1JmIl18tm1AkiIl18tm1AkiIl18tm1AkiIl12btm1Jm

decreased interferon-gamma secretion_Il12b<tm1Jm>/Il12b<tm1Jm>,Il18<tm1Aki>/Il18<tm1Aki>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 18
  http://metadb.riken.jp/db/mgi_rdf/MGI:107936
• interleukin 12b
  http://metadb.riken.jp/db/mgi_rdf/MGI:96540

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il12b<tm1Jm>/Il12b<tm1Jm>,Il18<tm1Aki>/Il18<tm1Aki>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il18<tm1Aki>|Il12b<tm1Jm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/SvImJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008567

文献

http://purl.org/net/cito/citesAsAuthority

• K. Takeda, et.al., Defective NK cell activity and Th1 response in IL-18-deficient mice., Immunity, 1998, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9529155