decreased interferon-gamma secretion_Tyk2<tm1Shmd>/Tyk2<tm1Shmd>

http://metadb.riken.jp/0008567I129P2OlaHsdTyk2tm1ShmdTyk2tm1ShmdTyk2tm1Shmd

decreased interferon-gamma secretion_Tyk2<tm1Shmd>/Tyk2<tm1Shmd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tyrosine kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929470

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tyk2<tm1Shmd>/Tyk2<tm1Shmd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tyk2<tm1Shmd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008567

文献

http://purl.org/net/cito/citesAsAuthority

• K. Shimoda, et.al., Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function., Immunity, 2000, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/11070174