decreased interferon-gamma secretion_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>,Mir146<tm1.1Bal>/Mir146<tm1.1Bal>

http://metadb.riken.jp/0008567I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrMir146tm11BalMir146tm11BalMir146tm11BalFoxp3tm11Ayr

decreased interferon-gamma secretion_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>,Mir146<tm1.1Bal>/Mir146<tm1.1Bal>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• microRNA 146
  http://metadb.riken.jp/db/mgi_rdf/MGI:2676831

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>,Mir146<tm1.1Bal>/Mir146<tm1.1Bal>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mir146<tm1.1Bal>|Foxp3<tm1.1Ayr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interferon-gamma secretion
  http://purl.obolibrary.org/obo/MP_0008567

文献

http://purl.org/net/cito/citesAsAuthority

• Li-Fan. Lu, et.al., Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses., Cell, 2010, 142
  http://rdf.ncbi.nlm.nih.gov/pubmed/20850013