abnormal synaptic bouton morphology_Tg(Hmgcr-PSEN1*M146L)#Lpr/0,Tg(Thy1-APP<SL>)28Lpr/0

http://metadb.riken.jp/0008571IC57BL6CBATgHmgcrPSEN1M146LLpr0TgThy1APPSL28Lpr0TgHmgcrPSEN1M146LLprTgThy1APPSL28Lpr

abnormal synaptic bouton morphology_Tg(Hmgcr-PSEN1*M146L)#Lpr/0,Tg(Thy1-APP<SL>)28Lpr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Laurent Pradier
  http://metadb.riken.jp/db/mgi_rdf/MGI:5003457
• transgene insertion 28, Laurent Pradier
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510602

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Hmgcr-PSEN1*M146L)#Lpr/0,Tg(Thy1-APP<SL>)28Lpr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Hmgcr-PSEN1*M146L)#Lpr|Tg(Thy1-APP<SL>)28Lpr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal synaptic bouton morphology
  http://purl.obolibrary.org/obo/MP_0008571

文献

http://purl.org/net/cito/citesAsAuthority

• Bart P F. Rutten, et.al., Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice., The American journal of pathology, 2005, 167
  http://rdf.ncbi.nlm.nih.gov/pubmed/15972962