decreased circulating interferon-gamma level_Stat4<tm1Gru>/Stat4<tm1Gru>

http://metadb.riken.jp/0008578I129S2SvPasBALBcStat4tm1GruStat4tm1GruStat4tm1Gru

decreased circulating interferon-gamma level_Stat4<tm1Gru>/Stat4<tm1Gru>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat4<tm1Gru>/Stat4<tm1Gru>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat4<tm1Gru>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating interferon-gamma level
  http://purl.obolibrary.org/obo/MP_0008578

文献

http://purl.org/net/cito/citesAsAuthority

• Etienne. Richer, et.al., N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20693420