decreased circulating interferon-gamma level_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

http://metadb.riken.jp/0008578I129S2SvPasC57BL6Casp1tm1FlvCasp1tm1FlvCasp4delCasp4delCasp4delCasp1tm1Flv

decreased circulating interferon-gamma level_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96544
• caspase 4, apoptosis-related cysteine peptidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:107700

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp4<del>|Casp1<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating interferon-gamma level
  http://purl.obolibrary.org/obo/MP_0008578

文献

http://purl.org/net/cito/citesAsAuthority

• G. Fantuzzi, et.al., IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor., The Journal of clinical investigation, 1999, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/10491411