increased circulating interleukin-10 level_Stk11<tm1Keis>/Stk11<tm1Keis>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0008593I129P2OlaHsdStk11tm1KeisStk11tm1KeisLyz2tm1creIfoLyz2Stk11tm1KeisLyz2Lyz2tm1creIfo

increased circulating interleukin-10 level_Stk11<tm1Keis>/Stk11<tm1Keis>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• serine/threonine kinase 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341870
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stk11<tm1Keis>/Stk11<tm1Keis>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stk11<tm1Keis>|Lyz2<+>|Lyz2<tm1(cre)Ifo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-10 level
  http://purl.obolibrary.org/obo/MP_0008593

文献

http://purl.org/net/cito/citesAsAuthority

• Kirsty F. MacKenzie, et.al., PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway., Journal of immunology (Baltimore, Md. : 1950), 2013, 190
  http://rdf.ncbi.nlm.nih.gov/pubmed/23241891