increased circulating interleukin-6 level_Cry1<tm1Jhjh>/Cry1<tm1Jhjh>,Cry2<tm1Jhjh>/Cry2<tm1Jhjh>

http://metadb.riken.jp/0008596I129P2OlaHsdC57BL6Cry1tm1JhjhCry1tm1JhjhCry2tm1JhjhCry2tm1JhjhCry1tm1JhjhCry2tm1Jhjh

increased circulating interleukin-6 level_Cry1<tm1Jhjh>/Cry1<tm1Jhjh>,Cry2<tm1Jhjh>/Cry2<tm1Jhjh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cryptochrome 2 (photolyase-like)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270859
• cryptochrome 1 (photolyase-like)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270841

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cry1<tm1Jhjh>/Cry1<tm1Jhjh>,Cry2<tm1Jhjh>/Cry2<tm1Jhjh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cry1<tm1Jhjh>|Cry2<tm1Jhjh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-6 level
  http://purl.obolibrary.org/obo/MP_0008596

文献

http://purl.org/net/cito/citesAsAuthority

• Akira. Hashiramoto, et.al., Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha., Journal of immunology (Baltimore, Md. : 1950), 2010, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/20042581