increased circulating interleukin-6 level_Hmgb1<tm1.1Dltg>/Hmgb1<tm1.1Dltg>,Tg(Pdx1-cre)6Tuv/0

http://metadb.riken.jp/0008596IC57BL6FVBNHmgb1tm11DltgHmgb1tm11DltgTgPdx1cre6Tuv0Hmgb1tm11DltgTgPdx1cre6Tuv

increased circulating interleukin-6 level_Hmgb1<tm1.1Dltg>/Hmgb1<tm1.1Dltg>,Tg(Pdx1-cre)6Tuv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123
• high mobility group box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96113

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmgb1<tm1.1Dltg>/Hmgb1<tm1.1Dltg>,Tg(Pdx1-cre)6Tuv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hmgb1<tm1.1Dltg>|Tg(Pdx1-cre)6Tuv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-6 level
  http://purl.obolibrary.org/obo/MP_0008596

文献

http://purl.org/net/cito/citesAsAuthority

• Rui. Kang, et.al., Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice., Gastroenterology, 2014, 146
  http://rdf.ncbi.nlm.nih.gov/pubmed/24361123