increased circulating interleukin-18 level_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0008635I129P2OlaHsdHmgb1tm11TtgHmgb1tm11TtgLyz2tm1creIfoLyz2Hmgb1tm11TtgLyz2Lyz2tm1creIfo

increased circulating interleukin-18 level_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• high mobility group box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96113
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmgb1<tm1.1Ttg>/Hmgb1<tm1.1Ttg>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hmgb1<tm1.1Ttg>|Lyz2<+>|Lyz2<tm1(cre)Ifo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-18 level
  http://purl.obolibrary.org/obo/MP_0008635

文献

http://purl.org/net/cito/citesAsAuthority

• Hideyuki. Yanai, et.al., Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/24302768