increased circulating interleukin-18 level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

http://metadb.riken.jp/0008635I129S2SvPasC57BL6Casp1tm1SeshCasp1tm1SeshNlrp1aNeut1Nlrp1aNeut1Casp1tm1SeshNlrp1aNeut1

increased circulating interleukin-18 level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96544
• NLR family, pyrin domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684861

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp1<tm1Sesh>/Casp1<tm1Sesh>,Nlrp1a<Neut1>/Nlrp1a<Neut1>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp1<tm1Sesh>|Nlrp1a<Neut1>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating interleukin-18 level
  http://purl.obolibrary.org/obo/MP_0008635

文献

http://purl.org/net/cito/citesAsAuthority

• Seth L. Masters, et.al., NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells., Immunity, 2012, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/23219391