decreased interleukin-1 beta secretion_Casp1<tm1Sesh>/Casp1<+>,Casp4<del>/Casp4<+>

http://metadb.riken.jp/0008658I129S2SvPasC57BL6Casp1tm1SeshCasp1Casp4delCasp4Casp4delCasp1tm1SeshCasp4Casp1

decreased interleukin-1 beta secretion_Casp1<tm1Sesh>/Casp1<+>,Casp4<del>/Casp4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 4, apoptosis-related cysteine peptidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:107700
• caspase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96544

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp1<tm1Sesh>/Casp1<+>,Casp4<del>/Casp4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp4<del>|Casp1<tm1Sesh>|Casp4<+>|Casp1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-1 beta secretion
  http://purl.obolibrary.org/obo/MP_0008658

文献

http://purl.org/net/cito/citesAsAuthority

• P. Li, et.al., Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock., Cell, 1995, 80
  http://rdf.ncbi.nlm.nih.gov/pubmed/7859282