decreased interleukin-1 beta secretion_Nlrp3<tm1Tsc>/Nlrp3<tm1Tsc>

http://metadb.riken.jp/0008658IC57BL6Nlrp3tm1TscNlrp3tm1TscNlrp3tm1Tsc

decreased interleukin-1 beta secretion_Nlrp3<tm1Tsc>/Nlrp3<tm1Tsc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NLR family, pyrin domain containing 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653833

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nlrp3<tm1Tsc>/Nlrp3<tm1Tsc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nlrp3<tm1Tsc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-1 beta secretion
  http://purl.obolibrary.org/obo/MP_0008658

文献

http://purl.org/net/cito/citesAsAuthority

• Jae Jin. Chae, et.al., Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice., Immunity, 2011, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/21600797