decreased interleukin-10 secretion_Itk<tm1Ljb>/Itk<tm1Ljb>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

http://metadb.riken.jp/0008661I129C57BL10Itktm1LjbItktm1LjbRag1tm1MomRag1tm1MomTgTcra5CC7Tcrb5CC7IWepRag1tm1MomItktm1LjbTgTcra5CC7Tcrb5CC7IWep

decreased interleukin-10 secretion_Itk<tm1Ljb>/Itk<tm1Ljb>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• transgene insertion I, William E Paul
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761176
• IL2 inducible T cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96621

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itk<tm1Ljb>/Itk<tm1Ljb>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag1<tm1Mom>|Itk<tm1Ljb>|Tg(Tcra5CC7,Tcrb5CC7)IWep

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/10

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-10 secretion
  http://purl.obolibrary.org/obo/MP_0008661

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew T. Miller, et.al., Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet., Immunity, 2004, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/15345221