decreased interleukin-10 secretion_Tigit<tm1Sdl>/Tigit<tm1Sdl>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

http://metadb.riken.jp/0008661IC57BL6Tigittm1SdlTigittm1SdlTgTcra2D2Tcrb2D21Kuch0Tigittm1SdlTgTcra2D2Tcrb2D21Kuch

decreased interleukin-10 secretion_Tigit<tm1Sdl>/Tigit<tm1Sdl>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Vijay Kuchroo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3700835
• T cell immunoreceptor with Ig and ITIM domains
  http://metadb.riken.jp/db/mgi_rdf/MGI:3642260

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tigit<tm1Sdl>/Tigit<tm1Sdl>,Tg(Tcra2D2,Tcrb2D2)1Kuch/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tigit<tm1Sdl>|Tg(Tcra2D2,Tcrb2D2)1Kuch

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-10 secretion
  http://purl.obolibrary.org/obo/MP_0008661

文献

http://purl.org/net/cito/citesAsAuthority

• Nicole. Joller, et.al., Cutting edge: TIGIT has T cell-intrinsic inhibitory functions., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21199897