decreased interleukin-12 secretion_Cd86<tm1Shr>/Cd86<tm1Shr>,March1<tm1.1Sish>/March1<tm1.1Sish>

http://metadb.riken.jp/0008664I129S1Sv129S4SvJae129X1SvJCd86tm1ShrCd86tm1ShrMarch1tm11SishMarch1tm11SishMarch1tm11SishCd86tm1Shr

decreased interleukin-12 secretion_Cd86<tm1Shr>/Cd86<tm1Shr>,March1<tm1.1Sish>/March1<tm1.1Sish>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• membrane-associated ring finger (C3HC4) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920175
• CD86 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:101773

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd86<tm1Shr>/Cd86<tm1Shr>,March1<tm1.1Sish>/March1<tm1.1Sish>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• March1<tm1.1Sish>|Cd86<tm1Shr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-12 secretion
  http://purl.obolibrary.org/obo/MP_0008664

文献

http://purl.org/net/cito/citesAsAuthority

• Mari. Ohmura-Hoshino, et.al., Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19917682