increased interleukin-2 secretion_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008687I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr

increased interleukin-2 secretion_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T-box 21
  http://metadb.riken.jp/db/mgi_rdf/MGI:1888984
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Tbx21<tm2Srnr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008687

文献

http://purl.org/net/cito/citesAsAuthority

• Charlly. Kao, et.al., Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection., Nature immunology, 2011, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21623380