decreased interleukin-2 secretion_Cd28<tm1Pjl>/Cd28<tm1Pjl>,Tg(DO11.10)10Dlo/0

http://metadb.riken.jp/0008688I129P2OlaHsdC57BL6Cd28tm1PjlCd28tm1PjlTgDO111010Dlo0TgDO111010DloCd28tm1Pjl

decreased interleukin-2 secretion_Cd28<tm1Pjl>/Cd28<tm1Pjl>,Tg(DO11.10)10Dlo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 10, Dennis Y Loh
  http://metadb.riken.jp/db/mgi_rdf/MGI:2664401
• CD28 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd28<tm1Pjl>/Cd28<tm1Pjl>,Tg(DO11.10)10Dlo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(DO11.10)10Dlo|Cd28<tm1Pjl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• P J. Lucas, et.al., Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response., Journal of immunology (Baltimore, Md. : 1950), 1995, 154
  http://rdf.ncbi.nlm.nih.gov/pubmed/7751626