decreased interleukin-2 secretion_Fyb<tm1Gak>/Fyb<tm1Gak>

http://metadb.riken.jp/0008688I129S1Sv129X1SvJFybtm1GakFybtm1GakFybtm1Gak

decreased interleukin-2 secretion_Fyb<tm1Gak>/Fyb<tm1Gak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FYN binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fyb<tm1Gak>/Fyb<tm1Gak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fyb<tm1Gak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• Hongyan. Wang, et.al., Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17646386
• E J. Peterson, et.al., Coupling of the TCR to integrin activation by Slap-130/Fyb., Science (New York, N.Y.), 2001, 293
  http://rdf.ncbi.nlm.nih.gov/pubmed/11567141