decreased interleukin-2 secretion_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(GZMB-cre)1Jcb/0

http://metadb.riken.jp/0008688I129S4SvJaeFVBNPtentm1HwuPtentm1HwuTgGZMBcre1Jcb0Ptentm1HwuTgGZMBcre1Jcb

decreased interleukin-2 secretion_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(GZMB-cre)1Jcb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Joshy Jacob
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176190
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(GZMB-cre)1Jcb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Tg(GZMB-cre)1Jcb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• Timothy W. Hand, et.al., Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20823247