decreased interleukin-2 secretion_H2<b>/H2<b>,Nfkbid<tm1Clay>/Nfkbid<tm1Clay>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraN15,TcrbN15)L2Elre/?

http://metadb.riken.jp/0008688I129SSvEv129S6SvEvTacC57BL6H2bH2bNfkbidtm1ClayNfkbidtm1ClayRag2tm1FwaRag2tm1FwaTgTcraN15TcrbN15L2ElreH2bNfkbidtm1ClayRag2tm1FwaTgTcraN15TcrbN15L2Elre

decreased interleukin-2 secretion_H2<b>/H2<b>,Nfkbid<tm1Clay>/Nfkbid<tm1Clay>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraN15,TcrbN15)L2Elre/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion L2, Ellis L Reinherz
  http://metadb.riken.jp/db/mgi_rdf/MGI:3777748
• nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
  http://metadb.riken.jp/db/mgi_rdf/MGI:3041243
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<b>/H2<b>,Nfkbid<tm1Clay>/Nfkbid<tm1Clay>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraN15,TcrbN15)L2Elre/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2<b>|Nfkbid<tm1Clay>|Rag2<tm1Fwa>|Tg(TcraN15,TcrbN15)L2Elre

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• Maki. Touma, et.al., Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption., Journal of immunology (Baltimore, Md. : 1950), 2007, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/17641034