decreased interleukin-2 secretion_Stim1<tm1Rao>/Stim1<tm1Rao>,Stim2<tm1Rao>/Stim2<tm1Rao>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008688IC57BL6DBA2SJLStim1tm1RaoStim1tm1RaoStim2tm1RaoStim2tm1RaoTgCd4cre1Cwi0Stim1tm1RaoTgCd4cre1CwiStim2tm1Rao

decreased interleukin-2 secretion_Stim1<tm1Rao>/Stim1<tm1Rao>,Stim2<tm1Rao>/Stim2<tm1Rao>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• stromal interaction molecule 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107476
• stromal interaction molecule 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151156
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stim1<tm1Rao>/Stim1<tm1Rao>,Stim2<tm1Rao>/Stim2<tm1Rao>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stim1<tm1Rao>|Tg(Cd4-cre)1Cwi|Stim2<tm1Rao>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-2 secretion
  http://purl.obolibrary.org/obo/MP_0008688

文献

http://purl.org/net/cito/citesAsAuthority

• Masatsugu. Oh-Hora, et.al., Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18327260