decreased interleukin-4 secretion_Rad50<tm2.1Flv>/Rad50<tm2.2Flv>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008700I129S6SvEvTacC57BL6DBA2Rad50tm21FlvRad50tm22FlvTgCd4cre1Cwi0TgCd4cre1CwiRad50tm22FlvRad50tm21Flv

decreased interleukin-4 secretion_Rad50<tm2.1Flv>/Rad50<tm2.2Flv>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RAD50 double strand break repair protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:109292
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rad50<tm2.1Flv>/Rad50<tm2.2Flv>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Rad50<tm2.2Flv>|Rad50<tm2.1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-4 secretion
  http://purl.obolibrary.org/obo/MP_0008700

文献

http://purl.org/net/cito/citesAsAuthority

• Byung Hee. Koh, et.al., Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20483988