increased interleukin-6 secretion_Sigirr<tm1Mant>/Sigirr<tm1Mant>

http://metadb.riken.jp/0008705I129S1Sv129X1SvJC57BL6JSigirrtm1MantSigirrtm1MantSigirrtm1Mant

increased interleukin-6 secretion_Sigirr<tm1Mant>/Sigirr<tm1Mant>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344402

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sigirr<tm1Mant>/Sigirr<tm1Mant>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sigirr<tm1Mant>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-6 secretion
  http://purl.obolibrary.org/obo/MP_0008705

文献

http://purl.org/net/cito/citesAsAuthority

• Cecilia. Garlanda, et.al., Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/14993616