increased interleukin-6 secretion_Stat1<tm1Rds>/Stat1<tm1Rds>,Stat3<tm2Aki>/Stat3<tm2Aki>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0008705I129Sv129P2OlaHsdC57BL6Stat1tm1RdsStat1tm1RdsStat3tm2AkiStat3tm2AkiLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoStat1tm1RdsStat3tm2Aki

increased interleukin-6 secretion_Stat1<tm1Rds>/Stat1<tm1Rds>,Stat3<tm2Aki>/Stat3<tm2Aki>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• signal transducer and activator of transcription 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103063

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat1<tm1Rds>/Stat1<tm1Rds>,Stat3<tm2Aki>/Stat3<tm2Aki>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<+>|Lyz2<tm1(cre)Ifo>|Stat1<tm1Rds>|Stat3<tm2Aki>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased interleukin-6 secretion
  http://purl.obolibrary.org/obo/MP_0008705

文献

http://purl.org/net/cito/citesAsAuthority

• Masaya. Kobayashi, et.al., Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12727921