decreased interleukin-6 secretion_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)1Dv/0,Tg(Ins2-CD80)3B7Flv/0

http://metadb.riken.jp/0008706I129S2SvPasC57BL6C57BL10SnJCBAH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB11Dv0TgIns2CD803B7Flv0H2Ab1tm1GruTgHLADQA1HLADQB11DvTgIns2CD803B7Flv

decreased interleukin-6 secretion_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)1Dv/0,Tg(Ins2-CD80)3B7Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histocompatibility 2, class II antigen A, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103070
• transgene insertion 1, Chella David
  http://metadb.riken.jp/db/mgi_rdf/MGI:3586631
• transgene insertion 3B7, Richard Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046790

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)1Dv/0,Tg(Ins2-CD80)3B7Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2-Ab1<tm1Gru>|Tg(HLA-DQA1,HLA-DQB1)1Dv|Tg(Ins2-CD80)3B7Flv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased interleukin-6 secretion
  http://purl.obolibrary.org/obo/MP_0008706

文献

http://purl.org/net/cito/citesAsAuthority

• L. Wen, et.al., The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model., The Journal of clinical investigation, 2001, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/11285306