increased lung carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Scgb1a1<tm1.1(cre)Fjd>/Scgb1a1<+>

http://metadb.riken.jp/0008714I129S1Sv129S4SvJae129X1SvJKrastm4TyjKrasPtentm1HwuPtentm1HwuScgb1a1tm11creFjdScgb1a1Scgb1a1tm11creFjdKrasKrastm4TyjScgb1a1Ptentm1Hwu

increased lung carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Scgb1a1<tm1.1(cre)Fjd>/Scgb1a1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• secretoglobin, family 1A, member 1 (uteroglobin)
  http://metadb.riken.jp/db/mgi_rdf/MGI:98919

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Scgb1a1<tm1.1(cre)Fjd>/Scgb1a1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scgb1a1<tm1.1(cre)Fjd>|Kras<+>|Kras<tm4Tyj>|Scgb1a1<+>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0008714

文献

http://purl.org/net/cito/citesAsAuthority

• Kentaro. Iwanaga, et.al., Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer., Cancer research, 2008, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/18281487