increased lung non-small cell carcinoma incidence_Kras<tm1Bbd>/Kras<+>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>

http://metadb.riken.jp/0008716I129Sv129S1Sv129X1SvJKrastm1BbdKrasMapk3tm1GpgMapk3tm1GpgMapk3tm1GpgKrastm1BbdKras

increased lung non-small cell carcinoma incidence_Kras<tm1Bbd>/Kras<+>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346859
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm1Bbd>/Kras<+>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk3<tm1Gpg>|Kras<tm1Bbd>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung non-small cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0008716

文献

http://purl.org/net/cito/citesAsAuthority

• Rafael B. Blasco, et.al., c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma., Cancer cell, 2011, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21514245