impaired neutrophil chemotaxis_Rasgrp4<tm1d(KOMP)Lste>/Rasgrp4<tm1d(KOMP)Lste>

http://metadb.riken.jp/0008720I129S4SvJaeSorBALBcJC57BL6Rasgrp4tm1dKOMPLsteRasgrp4tm1dKOMPLsteRasgrp4tm1dKOMPLste

impaired neutrophil chemotaxis_Rasgrp4<tm1d(KOMP)Lste>/Rasgrp4<tm1d(KOMP)Lste>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RAS guanyl releasing protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rasgrp4<tm1d(KOMP)Lste>/Rasgrp4<tm1d(KOMP)Lste>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rasgrp4<tm1d(KOMP)Lste>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired neutrophil chemotaxis
  http://purl.obolibrary.org/obo/MP_0008720

文献

http://purl.org/net/cito/citesAsAuthority

• Sabine. Suire, et.al., GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4., The EMBO journal, 2012, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/22728827