decreased susceptibility to endotoxin shock_Itgal<tm1Mak>/Itgal<tm1Mak>

http://metadb.riken.jp/0008734B6129P2Itgaltm1MakItgaltm1MakItgaltm1MakItgaltm1Mak

decreased susceptibility to endotoxin shock_Itgal<tm1Mak>/Itgal<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin alpha L
  http://metadb.riken.jp/db/mgi_rdf/MGI:96606

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgal<tm1Mak>/Itgal<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgal<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129P2-Itgal<tm1Mak>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Masashi. Emoto, et.al., Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balance., Journal of immunology (Baltimore, Md. : 1950), 2003, 171
  http://rdf.ncbi.nlm.nih.gov/pubmed/12847222