decreased susceptibility to endotoxin shock_Ccr5<tm1Brv>/Ccr5<tm1Brv>

http://metadb.riken.jp/0008734EI129S1SvICRorI129S1Sv129X1SvJICRCcr5tm1BrvCcr5tm1BrvCcr5tm1Brv

decreased susceptibility to endotoxin shock_Ccr5<tm1Brv>/Ccr5<tm1Brv>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-C motif) receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:107182

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccr5<tm1Brv>/Ccr5<tm1Brv>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ccr5<tm1Brv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S1/Sv * ICR) or (involves: 129S1/Sv * 129X1/SvJ * ICR)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Y. Zhou, et.al., Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor., Journal of immunology (Baltimore, Md. : 1950), 1998, 160
  http://rdf.ncbi.nlm.nih.gov/pubmed/9558111