decreased susceptibility to endotoxin shock_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0008734I129C57BL6Socs3tm1AyosSocs3tm1AyosLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Socs3tm1Ayos

decreased susceptibility to endotoxin shock_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• suppressor of cytokine signaling 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201791
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Socs3<tm1Ayos>/Socs3<tm1Ayos>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lyz2<+>|Socs3<tm1Ayos>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Hideo. Yasukawa, et.al., IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages., Nature immunology, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/12754507