decreased susceptibility to endotoxin shock_Il6st<tm1Ern>/Il6st<tm1Ern>,Stat3<tm1Aki>/Stat3<+>

http://metadb.riken.jp/0008734I129P2OlaHsd129S1SvIl6sttm1ErnIl6sttm1ErnStat3tm1AkiStat3Il6sttm1ErnStat3tm1AkiStat3

decreased susceptibility to endotoxin shock_Il6st<tm1Ern>/Il6st<tm1Ern>,Stat3<tm1Aki>/Stat3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• interleukin 6 signal transducer
  http://metadb.riken.jp/db/mgi_rdf/MGI:96560

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6st<tm1Ern>/Il6st<tm1Ern>,Stat3<tm1Aki>/Stat3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6st<tm1Ern>|Stat3<tm1Aki>|Stat3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Claire J. Greenhill, et.al., IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148800