decreased susceptibility to endotoxin shock_Il6st<tm1Ern>/Il6st<tm1Ern>,Tirap<tm1.1Pjh>/Tirap<tm1.1Pjh>

http://metadb.riken.jp/0008734I129S1SvIl6sttm1ErnIl6sttm1ErnTiraptm11PjhTiraptm11PjhIl6sttm1ErnTiraptm11Pjh

decreased susceptibility to endotoxin shock_Il6st<tm1Ern>/Il6st<tm1Ern>,Tirap<tm1.1Pjh>/Tirap<tm1.1Pjh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152213
• interleukin 6 signal transducer
  http://metadb.riken.jp/db/mgi_rdf/MGI:96560

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6st<tm1Ern>/Il6st<tm1Ern>,Tirap<tm1.1Pjh>/Tirap<tm1.1Pjh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6st<tm1Ern>|Tirap<tm1.1Pjh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Claire J. Greenhill, et.al., IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148800