decreased susceptibility to endotoxin shock_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>,Il1r1<tm1Imx>/Il1r1<tm1Imx>

http://metadb.riken.jp/0008734I129S2SvPas129S7SvEvBrdC57BL6Casp1tm1FlvCasp1tm1FlvCasp4delCasp4delIl1r1tm1ImxIl1r1tm1ImxCasp1tm1FlvCasp4delIl1r1tm1Imx

decreased susceptibility to endotoxin shock_Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>,Il1r1<tm1Imx>/Il1r1<tm1Imx>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 1 receptor, type I
  http://metadb.riken.jp/db/mgi_rdf/MGI:96545
• caspase 4, apoptosis-related cysteine peptidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:107700
• caspase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96544

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp1<tm1Flv>/Casp1<tm1Flv>,Casp4<del>/Casp4<del>,Il1r1<tm1Imx>/Il1r1<tm1Imx>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp1<tm1Flv>|Casp4<del>|Il1r1<tm1Imx>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• M B. Glaccum, et.al., Phenotypic and functional characterization of mice that lack the type I receptor for IL-1., Journal of immunology (Baltimore, Md. : 1950), 1997, 159
  http://rdf.ncbi.nlm.nih.gov/pubmed/9317135