decreased susceptibility to endotoxin shock_Irak1<tm1Jth>/Y,Irak2<tm1Aki>/Irak2<tm1Aki>

http://metadb.riken.jp/0008734I129SvC57BL6Irak1tm1JthYIrak2tm1AkiIrak2tm1AkiIrak2tm1AkiIrak1tm1Jth

decreased susceptibility to endotoxin shock_Irak1<tm1Jth>/Y,Irak2<tm1Aki>/Irak2<tm1Aki>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin-1 receptor-associated kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107420
• interleukin-1 receptor-associated kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429603

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irak1<tm1Jth>/Y,Irak2<tm1Aki>/Irak2<tm1Aki>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irak2<tm1Aki>|Irak1<tm1Jth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008734

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsukata. Kawagoe, et.al., Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18438411