increased susceptibility to endotoxin shock_Il10<tm1Cgn>/Il10<tm1Cgn>

http://metadb.riken.jp/0008735I129P2OlaHsdIl10tm1CgnIl10tm1CgnIl10tm1Cgn

increased susceptibility to endotoxin shock_Il10<tm1Cgn>/Il10<tm1Cgn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 10
  http://metadb.riken.jp/db/mgi_rdf/MGI:96537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il10<tm1Cgn>/Il10<tm1Cgn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il10<tm1Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008735

文献

http://purl.org/net/cito/citesAsAuthority

• Lisa. Siewe, et.al., Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA., European journal of immunology, 2006, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/17111348
• Michael. Hammer, et.al., Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock., The Journal of experimental medicine, 2006, 203
  http://rdf.ncbi.nlm.nih.gov/pubmed/16380512